rankydiava2sw0 rankydiava2sw0
  • 21-02-2017
  • Biology
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Why are microdeletions and microinsertions difficult to diagnose?

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BioWizard
BioWizard BioWizard
  • 06-07-2018
Microdeletions are very small a chromosomal deletion, usually smaller than 5 million base pairs (5 Mb). Because of that, it is hard to detect it by conventional cytogenetic methods ( through a microscope). Thus, the technique used for detection is high-resolution chromosome banding done by fluorescence in situ hybridization (FISH). The same thing is with microinsertions.
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