Answer:
It might have the negative effect of, after a failed hunt of a larger prey, it might have difficulty hunting after that, either by due to lack of energy or lack of food, which is basically the same
When hunting a larger prey the lion might have problems overpowering the prey and/or tackling it. When hunting smaller preys, it also has its drawbacks, sure, the lion might attack it and bring it down easily but it might be faster than said lion so it's always a gamble for a lion to hunt alone
